Fire up VLC, grab the HI pack, and listen to House tell the patient they have "Autoimmune Hemolytic Anemia" while reading the exact spelling. That is the top experience.
If you download a subtitle file (.SRT) and it doesn't match your video, you don't necessarily need a new file. Most "top" subtitle users utilize these tricks:
Whether you are rewatching "Three Stories" (S1E21) or crying through the series finale "Everybody Dies" (S8E22), let the words on the screen match the genius of the performance. Download the top subs, sync them once, and enjoy Princeton-Plainsboro Teaching Hospital like never before.