: Examination of how different metabolic pathways interact to maintain cellular energy and homeostasis. Muslim Institute of Higher Education Educational Design Medical Biochemistry - Muslim Institute of Higher Education
EPHX1 is a homodimeric enzyme primarily located in the of liver cells, though it is also present in kidneys, lungs, and testes. Each subunit (~53 kDa) contains an alpha/beta hydrolase fold, with a catalytic triad— Asp226, His431, and Asp495 —that is essential for activity. Unlike cytochrome P450s (which generate epoxides), EPHX1 acts on existing epoxide substrates. ephti biochemistry pdf