Some works of fantasy or fiction explore themes of human-animal transformation or connection, often serving as metaphors for human relationships or conditions.

In literature and cinema, the portrayal of beastiality and animal-human relationships can range from the symbolic to the explicit. Works like The Metamorphosis by Franz Kafka, where the protagonist transforms into a beetle, explore themes of isolation and the human condition through a physical transformation into an animal. While not explicitly about beastiality, these narratives use the human-animal dynamic to probe psychological and social issues.

Throughout history, tales of humans interacting with animals have been present in various cultures, sometimes blurring the lines between reality and fantasy. For example, Greek mythology includes stories of gods transforming into animals and interacting with humans, which have been interpreted in many ways over the centuries.