Associated genes: WT1 (11p13), WT2 (11p15), CTNNB1 , and TP53 .
: 90% are unilateral; 10% are bilateral or multifocal (suggesting germline mutations). 🩺 Clinical Presentation wilms tumor ppt new
Residual non-hematogenous tumor in the abdomen (e.g., lymph node involvement or tumor spill). Stage IV: Hematogenous metastases (usually lungs or liver). Stage V: Bilateral renal involvement. 5. Management & Treatment Associated genes: WT1 (11p13), WT2 (11p15), CTNNB1 ,