Pixels of Perception: The Impact of Rasterization on Chemical Data Integrity and Interpretability

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If you aren't sure of the source or don't have the original software, universal online converters can sometimes handle these files, though support for CDX is less common than for standard image types.

If you have access to ChemDraw (or ChemSketch), this is the superior method. It ensures the resulting JPG has high resolution and accurately represents the chemical structure.