– Always. Save files are in Documents/My Games/Binding of Isaac Repentance/ . Copy the rep_persistentgamedata.dat file elsewhere.
-exclusive content (like Tainted characters and the "Dead God" achievement) left to explore. Achievement Requirements Binding Of Isaac Repentance 1001 Save File
: To earn the 1001% achievement traditionally, a player had to unlock every secret, collect every item added through the Afterbirth – Always