The Medcurso 2015 system was typically divided into multiple modules, corresponding to the major medical specialties. The physical characteristics of the booklets were distinct:

| | Key Topics in 2015 Edition | Notable Protocols (2015 Context) | | :--- | :--- | :--- | | Infectious Diseases | Dengue, Zika (emerging), Pneumonia, HIV | Prior to major Zika outbreak in Brazil; ART regimens pre-Dolutegravir dominance. | | Cardiology | Acute MI, Heart Failure, Arrhythmias | Use of 3rd vs. 4th generation stents; emphasis on ESC and AHA guidelines 2014 . | | Pediatrics | Vaccination schedules, Neonatal ICU | Pre- meningococcal C widespread catch-up campaign in some states. | | Surgery | Trauma (ATLS principles), Appendicitis | Open vs. laparoscopic cholecystectomy standards. | | Preventive Med | SUS (Unified Health System) laws, Epidemiology | Specific laws (8080/8142) unchanged, but statistical techniques (SPSS/R) were less emphasized. |

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: Extensive volumes covering Internal Medicine, Surgery, Pediatrics, OB/GYN, and Preventive Medicine. ⚠️ Challenges of Using the 2015 Edition Today

The 2015 work represented a maturation of their methodology. It was the first year where the apostilas felt fully optimized for the "active recall" method. Unlike earlier versions that were dense walls of text, or later versions (post-2018) that became increasingly image-heavy and bullet-pointed, the 2015 edition struck a rare balance.

Furthermore, the 2015 edition coincided with updates in several major international medical guidelines. As medical guidelines change (e.g., changes in hypertension management by the ACC/AHA), the value of these specific 2015 booklets depreciates over time regarding clinical practice. However, they remain historically relevant as a snapshot of the medical consensus of that year and as a foundation for understanding the evolution of residency exams in Brazil.